What is NASH?

The rising incidence of fatty liver disease is closely mirroring the global epidemics of obesity and type 2 diabetes.1

Nonalcoholic steatohepatitis (NASH) is a more advanced form of fatty liver disease where the liver has a high level of fat and there is inflammation and damage (scarring).2

Although the cause is unknown, NASH is more likely to occur in people who are overweight or obese, have type 2 diabetes, high blood pressure, high cholesterol or high triglycerides (a type of fat in the blood).6

To date, no specific treatment for NASH is available.7

Find out more about NASH and why it is becoming a major worldwide concern.


1. Shetty A & Syn W-K. Fed Pract 2019; 36(1): 14-19. 2. Nonalcoholic Fatty Liver Disease. American Liver Foundation. Available at: https://liverfoundation.org/for-patients/about-the-liver/diseases-of-the-liver/non-alcoholic-fatty-liver-disease/ Accessed March 2020. 3.Younossi ZM. J Hepatol 2019; 70: 531-544. 4. Spengler EK & Loomba R. Mayo Clin Proc 2015; 90(9): 1233-1246. 5. One percent of the world's population. Available at: https://www.quora.com/How-many-people-are-one-percent-of-the-worlds-population Accessed March 2020. 6. NASH Causes and Risk Factors. American Liver Foundation. Available at: https://liverfoundation.org/for-patients/about-the-liver/diseases-of-the-liver/nonalcoholic-steatohepatitis-information-center/nash-causes-risk-factors/ Accessed March 2020. 7. Chopra S. Patient education: Nonalcoholic fatty liver disease (NAFLD), including non-alcoholic steatohepatitis (NASH) (Beyond the Basics). UpToDate.com. Available at: https://www.uptodate.com/contents/nonalcoholic-fatty-liver-disease-nafld-including-nonalcoholic-steatohepatitis-nash-beyond-the-basics Accessed March 2020.